Research Group Resilience and Brain Reorganisation for Individualised Recovery (REWIRE)

The distinctive feature of REWIRE is the study of neurological disease not only from the perspective of brain damage, but also from the perspective of the brain’s capacity to resist, compensate, reorganise and recover. This framework allows us to integrate conditions and scientific questions traditionally addressed in isolation — stroke, brain injury, neurodegeneration, cognition, language and rehabilitation — within a cross-cutting question:

What determines whether a brain is capable of maintaining or regaining its function in the face of an injury, a disease or a change in its usual conditions?

Answering this question requires integrating information on the injury and the condition with the brain’s pre-existing organisation, the connectivity of neural networks, individual factors and mechanisms of plasticity. The group thus aims to bridge the gap between fundamental neuroscience and clinical practice, generating knowledge that can be translated into better tools for the diagnosis, prognosis and treatment of neurological diseases.

The group’s interdisciplinary nature facilitates collaboration with the fields of Neurology, Neurosurgery, Radiology, Rehabilitation, Geriatrics, Psychology, Neuropsychology, Biomedical Engineering, Data Science and Cognitive Neuroscience, thereby fostering the development of multidisciplinary projects within the Faculty of Medicine and Health Sciences. Furthermore, the combination of clinical cohorts, advanced neuroimaging, cognitive assessment and multimodal analysis provides a solid foundation for participation in competitive national and international projects focused on precision medicine, neurological biomarkers and brain recovery.